Alcohol Use and Kidney Disease
top of page

Alcohol Use and Kidney Disease


While a few occasional drinks may not have a major impact on a person's health, alcohol consumption and addiction can affect the kidneys and even exacerbate kidney disease. Drinking too much alcohol can also lead to high blood pressure, which increases the risk of kidney disease. If you have high blood pressure, you should pay special attention to how alcohol affects your kidneys and overall health.

Even in a very healthy person, drinking too much alcohol can lead to heart disease, liver disease, high blood pressure, and kidney disease, among many other health problems. Last but not least, alcohol causes liver disease, which in turn increases the workload of the kidneys. While many other factors, such as family history and lifestyle, can also affect the likelihood of developing kidney disease, alcohol greatly increases a person's susceptibility to the disease. In fact, the majority of patients in the United States with both liver disease and related renal dysfunction are alcohol-dependent.

Clinical studies have shown that moderate alcohol consumption is associated with a lower incidence of CKD, and alcohol consumption can reduce the deterioration of renal function. This population-based cohort study was unable to determine whether there was an inverse relationship between alcohol consumption and renal function in patients with chronic kidney disease stages 3-5. The strength of the study is that it provides a comprehensive analysis of several aspects of renal function decline associated with drinking patterns, including alcohol consumption and frequency. Although they found that alcohol consumption is beneficial to kidney function, the findings should not be used to encourage or demonstrate that excessive alcohol consumption is beneficial to kidney health because of the many other known medical or social problems associated with alcohol consumption, especially excessive alcohol consumption.

Alcohol Consumption and Chronic Renal Failure


The finding of an inverse relationship between alcohol consumption and chronic renal failure is consistent with previous studies, although these other studies used different criteria for classifying kidney disease. Based on our finding of an inverse relationship between alcohol consumption and CKD, and the availability of many previous studies documenting the beneficial effects of moderate alcohol consumption on cardiovascular health, it is reasonable to recommend moderate drinking with caution. Drinking alcohol is generally safe in moderation, even if you have chronic kidney disease, polycystic kidney disease, end stage kidney disease (ESRD), or diabetes.

Excessive drinking has been linked to several health problems, including an increased risk of liver disease and certain cancers (not to mention the risk of drinking driving accidents while intoxicated. Alcohol, especially when consumed in excess, can negatively affect many body systems. Drinking alcohol dehydrates the body, which can adversely affect the function of the kidneys and other vital organs. When alcohol dehydrates (dries) the body, the dehydration effects affect the normal function of cells and organs, including the kidneys.

When drinking alcohol, the kidneys cannot maintain a normal level of water in the body, which can adversely affect other organs and cells of the body. Alcohol can change the function of the kidneys and make them less able to filter blood. In addition to filtering blood, your kidneys perform many other important functions.

Continued drinking can overload the kidneys and reduce their function. Excessive drinking can cause a person's blood alcohol levels to rise to dangerous levels, which in turn can cause the kidneys to lose function, to a level known as acute kidney injury. One of the most common causes of kidney damage and alcohol-related disease is heavy drinking. One form of alcoholism that can lead to kidney disease is binge drinking, usually defined as four or five drinks within two hours.

Treatment or prevention of kidney damage or diseases caused by chronic alcohol use often involves seeking treatment for alcohol use and alcohol dependence. Treatment and counseling for alcoholism may also be needed to manage kidney failure and disease caused by excessive drinking.


Alcohol Consumption and the Causes of Kidney Pain

According to some kidney specialists, there are no studies to support a link between alcohol and kidney pain. There is minimal evidence that alcohol increases the risk of kidney stones or kidney infections. Experimental data confirm the direct and acute nephrotoxic effect of alcohol on the kidneys; alternatively, chronic use in humans can cause alcohol-induced hypertension, indirectly increasing the risk of chronic kidney disease.

The effect of alcohol consumption on patients with chronic renal failure cannot simply be explained by the effects of ethanol and its metabolites on the kidneys; the effect of other bio activators in alcohol and the effect of alcohol consumption on other body systems should also be taken into account. In healthy Japanese men, an inverse relationship was found between the frequency of alcohol consumption and CKD.

In addition to the short-term effects on the body, chronic alcohol consumption can have many long-term effects on the body, especially on the brain, kidneys, and liver. Additionally, excessive drinking can lead to inflammation of the liver, called alcoholic hepatitis, which can eventually lead to permanent damage, including an enlarged liver, scarring, or cirrhosis, which can lead to cancer and even death. In addition to causing high blood pressure, alcohol can interfere with some high blood pressure medications. Alcohol increases the acidity of urine and can irritate the lining of the bladder.

While drinking a glass of wine or a cocktail from time to time usually doesn't do much harm, drinking too much alcohol can affect your overall health and well-being.

While the exact role of the inflammatory response is unknown, it plays a key role in alcohol-induced kidney damage. Other animal studies have shown that alcohol prevents the development of renal ischemia/reperfusion injury, reduces renal arteriole hyaline independent of its effect on other cardiovascular risk factors, and prevents renal small Arterial clearing. Recruitment of leukocytes and impairment of the endothelial barrier.


Although alcohol use and the damage it may cause may be minimal it is also important to understand the effects of alcohol and your medications. It is always encouraged advised and recommended by kidney conversations to speak with your medical team in regards to your use of alcohol.









Cited Sources
• https://www.kidney.org/atoz/content/alcohol 0
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767945/ 1
• https://www.durhamnephrology.com/how-alcohol-affects-your-kidneys/ 2
• https://academic.oup.com/ndt/article/24/8/2464/1940047 3
• https://www.pharmacytimes.com/view/heavy-alcohol-use-accelerates-ckd-progression 4
• https://www.medicalnewstoday.com/articles/326159 5
• https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1152793 6
• https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203410 7
• https://physiciansallianceofconnecticut.com/blog/long-term-effects-of-alcohol-on-the-brain-kidney-and-liver/ 8
• https://vertavahealth.com/alcohol/kidneys/ 9
• https://bmcnephrol.biomedcentral.com/articles/10.1186/1471-2369-14-254 10
• https://www.alcohol.org/effects/kidney-disease/ 11
• https://www.davita.com/diet-nutrition/articles/advice/alcohol-and-chronic-kidney-disease 12
• https://health.clevelandclinic.org/how-alcohol-affects-your-kidney-health/ 13
• https://www.mayoclinicproceedings.org/article/S0025-6196(19)30630-5/fulltext 14
• https://www.summitmedicalclinic.com/how-alcohol-affects-your-kidneys/ 15
• https://www.nature.com/articles/s41598-021-81777-5 16


990 views0 comments
bottom of page